Ultra Calm


Improve your mood.

Pure Essentials Ultra Calm is a natural alternative to prescription drugs, featuring a synergy of nutrients that are essential for mental and emotional wellbeing. With its free form, active ingredients, it additionally supports the elimination of toxic build-up in your system, further stabilizing your body-mind balance.

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  • Benefits
  • Nutrients
  • Dosage
  • References


Glycine, an amino acid that is used by the brain as a control neurotransmitter, regulates sleep rhythms, thereby producing calmness and aiding sleep. It also sustains the phase II detoxification pathway in the liver, which neutralizes and clears toxins.

Magnesium is a mineral that is required for proper nerve transmission. An adequate magnesium level is necessary for maintaining normal mood levels and preventing nerve irritability. In a random, double-blind study, researchers evaluated the effects of magnesium supplementation on premenstrual symptoms. During the trial, women were asked to fill out a questionnaire to document their symptoms. The researchers discovered that magnesium significantly affected test scores and concluded that magnesium supplementation could represent an effective treatment of premenstrual symptoms related to mood changes.

L-aspartate is another amino acid involved in brain and nervous system metabolism. This supplement is frequently recommended in its magnesium form for treating depression.


Two (2) Pure Essentials Ultra Calm capsules Provide:
Energized Nutrients
L-methionine (free) 500 mg
Glycine (free) 500 mg
L-aspartate (magnesium) 500 mg
Magnesium (as aspartate and as C16 and C18 alklys †) 25 mg
Vegetable fiber (organic croscarmellose) 100 mg
Kosher gelatin capsules 234 mg


As a dietary supplement, take two (2) capsules on an empty stomach upon rising and two (2) capsules before bed, or as directed by your health professional.


Bell KM, et al. S-adenosyl-Lmethionine blood levels in major depression: changes with drug treatment. Acta Neurol Scand Suppl. 1994;154:15-18.

Facchinetti F, et al. Oral magnesium successfully relieves pre-menstrual mood changes. Obstet Gynecol. 1991;78(2):177-181.

Frezza M, et al. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis: A double-blind, placebo-controlled study. Gastroenterology. 1990;99:211-215.

Kagan BL, et al. Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 1990;147(5):591-595.

Kakimoto H, et al. Changes in lipid composition of erythrocyte membranes with administration of S-adenosyl-L-methionine in chronic liver disease. Gastroenterolia Japonica. 1992;27:508-513.

Posaci C, et al. Plasma copper, zinc, and magnesium levels in patients with premenstrual tension syndrome. Acta Obstet Gynecol. 1994;73(6):452-455.
Ingredient Highlights


L-methionine is an amino acid that is key to maintaining clear detoxification pathways in the liver and brain. In the liver, L-methionine promotes liver health by promoting bile flow, improving membrane function and chelating heavy metals, which are documented contributors to mental and emotional disorders. In one random, double-blind, placebo-controlled trial, oral supplementation of S-adenosylmethionine (which converts into methionine in the body) significantly improved symptoms of major depression. Additional research shows that Pure Essentials Ultra Calm is superior to SAMe as a natural anti-depressant.