This product is new or has been recently improved. Please see more information here.
Prostate enlargement can affect several factors of men’s health including urinary flow and overall prostate health. Testosterone, its potent metabolite dihydrotestosterone (DHT), and estrogen are hormones that affect the prostate gland. Testosterone is converted into estrogen via the enzyme aromatase. Aromatase levels increase as men age resulting in a subsequent decline in testosterone levels and increased estrogen production. Testosterone is also converted to its more potent form, DHT, via the enzyme known as 5-alpha-reductase. The combination of increased estrogen levels along with elevated DHT is thought to be a key factor in enlargement of the prostate gland. Natural aromatase inhibitors and botanicals that prevent increased DHT and estrogen levels are included in Prostate Formula to help support healthy urinary flow, hormone metabolism, and overall prostate health.
Prostate Formula provides herbs and trace minerals that work in synergy to support healthy prostate function. Saw palmetto extract, nettles root extract, and pygeum bark extract each support prostate health in unique ways and work together to support healthy urinary flow, urination frequency, and maintain a balanced cycle of inflammation in the prostate.
• Helps Maintain Hormonal Balance
• Provides Nutrients that Support Prostate Health
2. Weisser H, et al. Effects of the sabal serrulata extract IDS 89 and its subfractions on 5 alpha-reductase activity in human benign prostatic hyperplasia. Prostate 1996; 28(5):300-306.
3. Carilla E, et al. Binding od Permixon, a new treatment for prostatic benign hyperplasia, to the cytosolic androgen receptor in rat prostate. J Steroid Biochem 1984; 20(1):521- 3.
4. Wilt TJ et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998; 280(6):1604-09.
5. Carraro JC et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1098 patients. Prostate 1996; 29(4):231-240.
6. Pizzorno JE. Murray MT. Textbook of Natural Medicine. 4th ed. Churchill Livingstone: St. Louis, MO. 2013.
7. Fischer M, Wilbert D. [Test of phytomedicine for treatment of benign prostatic hyperplasia (BPH).] In: Rutishager G, ed. Benigne Prostahyperplasie III: Klinische und experimentelle Urologie. Vol 22. New York: W Zuckswerdt; 1992:79-84.
8. Hryb DJ et al. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Medica 1995; 61(1):31-32.
9. Lichius JJ et al. The inhibiting effects of components of stinging nettle roots on experimentally induced prostatic hyperplasia in mice. Planta Medica 1999; 65(7):666-8.
10. Konrad L et al. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Medica 2000; 66(1):44-7.
11. Yablonsky F et al. Antiproliferative effect of Pygeum africanum extract on rat prostatic fibroblasts. J Urol 1997;157(6):2381-2387.
12. Paubert-Braquet M et al. Effect of Pygeum africanum extracts on A23187-stimulated production of lypoxygenase metabolites from human polymorphonuclear cells. J Lipid Mediat Cell Signal 1994; 9(3):285-290.
13. Breza J et al. Efficacy and acceptability of tadenan (Pygeum africanum extract) in the treatment of benign prostatic hyperplasia (BPH): a multicentre trial in central Europe. Curr Med Res Opin 1998; 14(3):127-39.
14. Chatelain C, Autet W, Brackman F. Comparison of once and twice daily dosage forms of Pygeum africanum extract in patients with benign prostatic hyperplasia: a randomized, double-blind study, with long-term open label extension. Urology 1999 54(3):473-8.
15. Sokeland J, Albrecht J. Combination of Sabal and Urtica extract vs. finasteride in benign prostatic hyperplasia (Aiken stages I to II). Comparison of therapeutic effectiveness in a one year double-blind study. Urology 1997;36(4):327-33.
16. Hartmann RW, Mark M, Soldati F. Inhibition of 5-a-reductase and aromatase by PHL-00801 a combination of PY102 (Pygeum africanum) and UR102 (Urtica dioica) extracts. Phytomedicine 1996; 3(2):121-128.
17. Leake A, Chisolm GD, Habib FK. The effect of zinc on the 5-alpha-reduction of testosterone by the hyperplastic human prostate gland. J Steroid Biochem 1984;20:651-5.